Pulmonary embolism, thrombocytopenia, and antiphospholipid syndrome.
نویسنده
چکیده
This case report describes a young non-smoker male masquerading under the diagnosis of community acquired pneumonia who was found to have respiratory symptoms attributed to bilateral pulmonary emboli. There was also evidence of thrombocytopenia and proximal deep venous thrombosis of right lower limb. He underwent further investigations and was found to have positive anti-cardiolipin antibodies, lupus anticoagulant and prolonged activated partial thromboplastin time due to antiphospholipid antibody syndrome. This article highlights the importance of consideration of earlier diagnosis in younger patients with congenital thrombophilias that carries potential for prevention and treatment of life threatening thromboembolic manifestations.
منابع مشابه
Double Thrombolysis with rt-PA in a Patient with Massive Pulmonary Embolism and Antiphospholipid Syndrome
T he antiphospholipid syndrome is an autoimmune disease, characterized by the presence of antiphospholipid antibodies, thromboses, repeat spontaneous abortions and thrombocytopenia. The syndrome may be encountered in patients without any clinical or laboratory indications of other systemic disease (primary), or may be encountered within the context of other systemic disease – more often with Sy...
متن کاملAntiprothrombin antibodies: detection and clinical significance in the antiphospholipid syndrome.
ANTIPHOSPHOLIPID antibodies have been associated with a variety of clinical phenomena, including arterial and venous thrombosis, thrombocytopenia, and obstetric complications. The term ‘‘antiphospholipid syndrome’’1 is used to link a variety of thromboembolic events to antibodies against specific proteins involved in blood coagulation. Thrombotic events are reported in approximately 30% of pati...
متن کاملRight atrial thrombus mimicking myxoma with pulmonary embolism in a patient with systemic lupus erythematosus and secondary antiphospholipid syndrome.
Antiphospholipid syndrome is a well-defined entity that is characterized by spontaneous abortion, thrombocytopenia, and recurrent arterial and venous thromboses. A partially calcified right atrial thrombus mimicking myxoma with recurrent pulmonary embolism has not been previously reported in a patient who also had systemic lupus erythematosus and secondary antiphospholipid syndrome. Herein, we ...
متن کاملRELISA CARDIOLIPIN IgG & IgM ANTIBODY TEST
Antiphospholipid antibodies, including anticardiolipin antibodies, are frequently detected in sera from patients with systemic lupus erythematosus (1). Numerous reports have associated these autoantibodies with various venous and arterial thrombotic disorders, including cerebral infarction (2), deep venous thrombosis (3), thrombocytopenia (1), pulmonary embolism (4), and recurrent fetal loss wi...
متن کاملUnusual manifestations of the antiphospholipid syndrome.
The classical clinical picture of the antiphospholipid syndrome (APS) is characterized by venous and arterial thromboses, fetal losses and thrombocytopenia, in the presence of antiphospholipid antibodies (aPL), namely lupus anticoagulant (LA), anticardiolipin antibodies (aCL), or antibodies to the protein "cofactor" b2 glycoprotein I. Single vessel involvement or multiple vascular occlusions ma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of Ayub Medical College, Abbottabad : JAMC
دوره 23 4 شماره
صفحات -
تاریخ انتشار 2011